Sue C Bodine Selected Research

Atrophy

12/2023	A critical discussion on the relationship between E3 ubiquitin ligases, protein degradation, and skeletal muscle wasting: it's not that simple.
10/2023	Impaired proteostatic mechanisms other than decreased protein synthesis limit old skeletal muscle recovery after disuse atrophy.
1/2022	The role of mTORC1 in the regulation of skeletal muscle mass.
12/2021	Activation of Crtc2/Creb1 in skeletal muscle enhances weight loss during intermittent fasting.
1/2021	Knockdown of the E3 ubiquitin ligase UBR5 and its role in skeletal muscle anabolism.
10/2020	Identification and characterization of Fbxl22, a novel skeletal muscle atrophy-promoting E3 ubiquitin ligase.
1/2020	Activating transcription factor 4 (ATF4) promotes skeletal muscle atrophy by forming a heterodimer with the transcriptional regulator C/EBPβ.
1/2020	Edward F. Adolph Distinguished Lecture. Skeletal muscle atrophy: Multiple pathways leading to a common outcome.
1/2019	UBR5 is a novel E3 ubiquitin ligase involved in skeletal muscle hypertrophy and recovery from atrophy.
1/2019	Skeletal Muscle Atrophy: Discovery of Mechanisms and Potential Therapies.

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Sue C Bodine Research Topics

Disease

22	Atrophy 12/2023 - 04/2002
18	Muscular Atrophy (Muscle Atrophy) 03/2024 - 02/2007
9	Hypertrophy 02/2024 - 05/2002
4	Atrophic Muscular Disorders 10/2023 - 10/2013
3	Insulin Resistance 12/2021 - 01/2016
3	Muscular Diseases (Myopathy) 10/2020 - 01/2018
1	Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy) 02/2024
1	Type 2 Diabetes Mellitus (MODY) 10/2022
1	Obesity 01/2021
1	Glucose Intolerance 01/2021
1	Cachexia 01/2015
1	Rheumatoid Arthritis 01/2015
1	Asthma (Bronchial Asthma) 01/2015
1	Neoplasms (Cancer) 01/2015
1	Starvation 01/2015
1	Sepsis (Septicemia) 01/2015
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2015
1	Spinal Cord Injuries (Spinal Cord Injury) 10/2013
1	Rotator Cuff Injuries 09/2012
1	Sciatic Neuropathy (Lesion of Sciatic Nerve) 05/2012
1	Neuromuscular Diseases (Neuromuscular Disease) 11/2007
1	Malnutrition (Nutritional Deficiencies) 06/2006

Drug/Important Bio-Agent (IBA)

21	Proteins (Proteins, Gene)FDA Link 03/2024 - 05/2002
9	UbiquitinIBA 03/2024 - 10/2008
7	Ligases (Synthetase)IBA 12/2023 - 10/2011
6	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 03/2024 - 10/2008
5	Proteasome Endopeptidase Complex (Proteasome)IBA 02/2024 - 10/2011
5	GlucocorticoidsIBA 12/2021 - 10/2008
3	Dexamethasone (Maxidex)FDA LinkGeneric 12/2013 - 10/2011
2	Mechanistic Target of Rapamycin Complex 1IBA 01/2022 - 08/2014
2	Glucose (Dextrose)FDA LinkGeneric 12/2021 - 01/2021
2	CarbohydratesIBA 12/2021 - 01/2016
2	Chloroquine (Aralen)FDA LinkGeneric 01/2020 - 01/2018
2	Messenger RNA (mRNA)IBA 01/2016 - 09/2014
2	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 05/2012 - 10/2008
2	ProteomeIBA 05/2002 - 04/2002
1	Deuterium Oxide (Heavy Water)IBA 10/2023
1	NitratesIBA 10/2022
1	NitritesIBA 10/2022
1	FatsIBA 12/2021
1	LipidsIBA 01/2021
1	Sucrose (Saccharose)IBA 01/2021
1	Protein Isoforms (Isoforms)IBA 10/2020
1	Leucine (L-Leucine)FDA Link 10/2020
1	CCAAT-Enhancer-Binding ProteinsIBA 01/2020
1	Basic-Leucine Zipper Transcription FactorsIBA 01/2020
1	Formoterol Fumarate (Oxis)FDA Link 01/2020
1	Activating Transcription Factor 4IBA 01/2020
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2020
1	Transcription Factors (Transcription Factor)IBA 01/2020
1	Colchicine FDA LinkGeneric 01/2018
1	Muscle Proteins (Muscle Protein)IBA 01/2016
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 08/2014
1	TOR Serine-Threonine KinasesIBA 05/2013
1	A-factor (Streptomyces)IBA 09/2012
1	Contractile ProteinsIBA 04/2012
1	Insulin-Like Growth Factor I (IGF-1)IBA 01/2008
1	Somatomedin Receptors (Somatomedin Receptor)IBA 01/2008
1	IGF Type 1 Receptor (IGF 1 Receptor)IBA 01/2008
1	ClenbuterolIBA 02/2007

Therapy/Procedure

6	Denervation 10/2020 - 02/2007
2	Therapeutics 01/2019 - 10/2013
1	Nerve Crush 01/2019
1	Bed Rest (Bedrest) 10/2013
1	Muscle Denervation 05/2012